- Maplebear Inc. D/B/A Instacart v. Consumeron, LLCAll claims unpatentablePTAB · Feb 29, 2024 · IPR2022-01357 · APJ Carl M Defranco · IPR · Final written decision
Claims 1, 2, 4, 6, 9, 10, 14–17, 21, 22, and 24–26 are unpatentable as obvious over the asserted combinations of Park, Kim, Hileman, Pugliese, and Mault.
RulingsFinal written decision- Claim Construction › Intrinsic evidence (Phillips canons) › Plain and ordinary meaning to a POSITATerm construed petitioner constructionDecided for petitioner
“does not equate an “acquisition request” exclusively with a shopping or purchase request. See Ex. 3006, 10–11. Rather, the specification repeatedly uses the phrase “purchase or otherwise acquire” to indicate that a delivery agent may acquire goods by means other than purchasing or shopping. See, e.g., Ex. 1001, 5:25–27 (“[T]he user specifies the exact location from which the selected delivery agent is to purchase or otherwise acquire the product, such as a retail store location.”); id. at 7:56–58 (“If the product is approved at 120, the delivery agent will purchase or otherwise acquire the product on behalf of the customer at 121.”); id. at 2:24–28 (“[T]he user provides the service provider with information regarding the type of product desired and the shopping or acquisition location from which the user desires to purchase or otherwise obtain the product.”) (emphases added). Consumeron’s argument that the specification “uses the word ‘or’ to refer to things that are synonymous to each other” is not persuasive. See PO Resp. 10; see also PO Sur-Reply 3–4 (essentially same). As noted above, the specification uses the phrase “purchase or otherwise acquire.” Ex. 1001, 5:25–27, 7:56–58 (emphasis added); see also id at 2:24–28 (similar). By including the adverb “otherwise,” the specification makes clear that purchase and acquire are not used synonymously, but rather that acquiring is broader and encompasses other ways of obtaining a product. See Ex. 1039, 1 (“otherwise” means “in a different way or manner”). Indeed, the specification unequivocally describes instances where the delivery agent acquires a product without purchasing or shopping for it. For instance, the specification explains that the customer may “pre-purchase[]” goods such that the customer requests simply that the delivery agent “pick-up” of the goods: [T]he customer has the option of paying the retailer or seller directly, in which case the customer will only be billed for the pick-up and delivery services provided. . . . If pre-purchased by the customer, the delivery agent obtains a receipt showing proof of pre-payment by the customer. Id. at 8:15–23 (emphases added). Even more explicitly, the specification states that, “although discussed in the context of a customer who wishes to purchase a product, it should be understood that system 10 may be utilized to schedule both pick-ups and delivery of any type of goods, including free goods. Id. at 10:40–44 (emphasis added). Those disclosures collectively indicate that a delivery agent can fulfill an acquisition request without necessarily shopping for or purchasing goods. Consumeron attempts to distinguish those descriptions, urging that they refer to an “alternative” embodiment that “does not expand the meaning of the term ‘acquisition request’ beyond its ordinary meaning.” PO Sur- Reply 4. But that argument is premised on an incorrect assumption that the ordinary meaning is limited to purchasing or shopping. Here, nothing in the intrinsic record suggests that the term “acquisition request” excludes the specification’s embodiments where “pre-purchased” or “free” goods are only in need of “pick-up.” To the contrary, as noted above, the specification repeatedly states the delivery agent may “otherwise acquire” goods without purchasing them, thereby, indicating that the agent can fulfill an acquisition request without necessarily shopping for the goods on the customer’s behalf. See Ex. 1001, 5:25–27, 7:56–58.” slip op. at 8
- Prior constructionPrior construction adoptedDecided for petitioner
“We previously construed the term “acquisition request” in the related 865 IPR to encompass “not only a request for an agent to shop for and purchase goods for delivery to a customer, but also to encompass a request for a delivery agent to simply pick up and deliver goods that have been prepurchased by the customer.” See Ex. 3006, 9–11 (granting institution in conjunction with construing “acquisition request”). As noted above in Section I.A (“Related Matters”), the 865 IPR centers on the ’465 patent, whose lineage derives from the same application—the ’867 application—as the ’835 patent challenged here. Compare Ex. 1001, 1:7–15 (referencing Appl. No. 12/711,867), with Ex. 3005, code (63) (also referencing Appl. No. 12/711,867). Indeed, the ’835 and ’465 patents share essentially identical specifications and figures. Thus, based on the final record before us (as discussed below) and consistent with our prior construction in the related 865 IPR, we likewise determine here that Instacart’s construction of “acquisition request” is the more reasonable one. See SightSound Techs., LLC v. Apple Inc., 809 F.3d 1307, 1316 (Fed. Cir. 2015) (“Where multiple patents ‘derive from the same parent application and share many common terms, we must interpret the claims consistently across all asserted patents.’” (quoting NTP, Inc., v. Research in Motion, Ltd., 418 F.3d 1282, 1293 (Fed. Cir. 2005)). More specifically, as we explained in the 865 IPR, the specification does not equate an “acquisition request” exclusively with a shopping or purchase request. See Ex. 3006, 10–11. Rather, the specification repeatedly uses the phrase “purchase or otherwise acquire” to indicate that a delivery agent may acquire goods by means other than purchasing or shopping. See, e.g., Ex. 1001, 5:25–27 (“[T]he user specifies the exact location from which the selected delivery agent is to purchase or otherwise acquire the product, such as a retail store location.”); id. at 7:56–58 (“If the product is approved at 120, the delivery agent will purchase or otherwise acquire the product on behalf of the customer at 121.”); id. at 2:24–28 (“[T]he user provides the service provider with information regarding the type of product desired and the shopping or acquisition location from which the user desires to purchase or otherwise obtain the product.”) (emphases added).” slip op. at 7
- Claim Construction › Threshold & procedure › Whether a term needs construction (O2 Micro)Term construed petitioner constructionDecided for petitioner
“Although the district court considered “intentional delay” in the course of construing the term “real time,” the district court does not appear to have accepted Consumeron’s narrower construction in that regard. More accurately, the district court stated it “sees no reason that a ‘real-time’ transmission of data could not both involve no inherent delay and permit a system that requires multiple ‘clicks’ to operate.” Ex. 1035, 24 (emphasis added). In addition, the district court quoted from a technical dictionary, which provided: The basic definition of real-time data is that it is data that is not kept or stored, but is passed along to the end user as quickly as it is gathered. It is important to note that real-time data does not mean that the data gets to the user instantly. There may be any number of bottlenecks related to the data collection infrastructure, the bandwidth between various parties, or even just the slowness of the end user’s computer. Real-time data does not promise data within a certain number of microseconds. It just means that the data is not designed to be kept back from its eventual use as it is collected. Id. at 25 (citing “Technopedia”). In other words, the district court contemplated that real-time data includes data that is transmitted as it is gathered despite some inherent delay in transmitting and accessing the data, such as bottlenecks in the infrastructure, slowness of the user’s computer, or “multiple clicks” by the user. With that in mind, we reject Consumeron’s attempt to alter our construction of “real-time” to exclude so-called “intentional delay.” Thus, consistent with the district court and our institution decision, we maintain that “real-time” transmission means “data that is passed along as it is gathered.”” slip op. at 12
- Skill levelSkill level petitioner adoptedDecided for petitioner
“Instacart submits that one skilled in the art would have had “a bachelor’s degree in electrical engineering, computer engineering, computer science, or equivalent training, and approximately two years of experience working in the field of electronic commerce” and that “[l]ack of work experience can be remedied by additional education, and vice versa. Pet. 14 (citing Ex. 1003 ¶ 24). Consumeron responds that one skilled in the art would have been “someone with a background in electrical engineering, computer science, or the like,” but that “industry experience can make up for a lack of technical training, and more education can make up for a lack of industry experience.” PO Resp. 9 (citing Ex. 2016 ¶¶ 17–20). 1 WO 01/11523 A1, published Feb. 15, 2001 (Ex. 1005) (“Park”). 2 Certified translation of KR2003-0085802, published Nov. 7, 2003 (Ex. 1006); corrected certified translation of Figure 2 (Ex. 1038); and original Korean language version (Ex. 1007) (collectively, “Kim”). 3 US 2003/0040944 A1, published Feb. 27, 2003 (Ex. 1009) (“Hileman”). 4 US 2002/0072974 A1, published June 13, 2002 (Ex. 1010) (“Pugliese”). 5 US 2002/0027164 A1, published Mar. 7, 2002 (Ex. 1016) (“Mault”). We discern no material difference between the levels of skill in the art espoused by the parties. Nor does Consumeron’s expert. See Ex. 2016 ¶ 20 (“Petitioner’s definition of a POSITA is not materially different from my definition.”). Accordingly, we adopt the level of skill in the art as defined by Instacart.” slip op. at 6
Patent outcomesUS 10,628,835 unpatentableClaim construction§ 103 obviousnesscites Phillips · KSRPatents in suitUS 10,628,835 - Maplebear Inc. D/B/A Instacart v. Consumeron, LLCAll claims unpatentablePTAB · Feb 29, 2024 · IPR2022-01356 · APJ Carl M Defranco · IPR · Final written decision
Claims 1, 4, 5, 8, 9, and 13–17 are unpatentable as obvious under § 103(a) over the grounds based on Park and Kim, with Hileman or Pugliese for specified dependent claims.
RulingsFinal written decision- Skill levelSkill level petitioner adoptedDecided for petitioner
“We discern no material difference between the levels of skill in the art espoused by the parties. Nor does Consumeron’s expert. See Ex. 2016 ¶ 20 (“Petitioner’s definition of a POSITA is not materially different from my definition.”). Accordingly, we adopt the level of skill in the art as defined by Instacart.” slip op. at 7
- Claim Construction › Intrinsic evidence (Phillips canons) › Plain and ordinary meaning to a POSITATerm construed petitioner constructionDecided for petitioner
“More specifically, as we explained in the 865 IPR, the specification does not equate an “acquisition request” exclusively with a shopping or purchase request. See Ex. 3006, 10–11. Rather, the specification repeatedly uses the phrase “purchase or otherwise acquire” to indicate that a delivery agent may acquire goods by means other than purchasing or shopping. See, e.g., Ex. 1001, 4:58–60 (“[T]he user specifies the exact location from which the selected delivery agent is to purchase or otherwise acquire the product, such as a retail store location.”); id. at 7:7–9 (“If the product is approved at 120, the delivery agent will purchase or otherwise acquire the product on behalf of the customer at 121.”); id. at 2:9–12 (“[T]he user provides the service provider with information regarding the type of product desired and the shopping or acquisition location from which the user desires to purchase or otherwise obtain the product.”) (emphases added).” slip op. at 8
- Prior constructionPrior construction adoptedDecided for petitioner
“course of construing “real time,” the district court does not appear to have accepted Consumeron’s narrower construction in that regard. More accurately, the district court stated it “sees no reason that a ‘real-time’ transmission of data could not both involve no inherent delay and permit a system that requires multiple ‘clicks’ to operate.” Ex. 1035, 24 (emphasis added). In addition, the district court quoted from a technical dictionary, which provided: The basic definition of real-time data is that it is data that is not kept or stored, but is passed along to the end user as quickly as it is gathered. It is important to note that real-time data does not mean that the data gets to the user instantly. There may be any number of bottlenecks related to the data collection infrastructure, the bandwidth between various parties, or even just the slowness of the end user’s computer. Real-time data does not promise data within a certain number of microseconds. It just means that the data is not designed to be kept back from its eventual use as it is collected. Id. at 25 (citing “Technopedia”). In other words, the district court contemplated that real-time data includes data that is transmitted as it is gathered despite some inherent delay in transmitting and accessing the data, such as bottlenecks in the infrastructure, slowness of the user’s computer, or “multiple clicks” by the user. With that in mind, we reject Consumeron’s attempt to alter our construction of “real-time” to exclude so-called “intentional delay.” Thus, consistent with the district court and our institution decision, we maintain that “real-time” transmission means “data that is passed along as it is gathered.” 3. “mobile delivery agent system” In our institution decision, we adopted a construction of “mobile delivery agent system” consistent with the way the term was construed in the Delaware action, namely, “a mobile system that includes at least a device to capture video or still images and a device set up to communicate with a remote server.” See Inst. Dec. 4–5 (citing Ex. 1034, 1; Ex. 1035, 13–17). Neither party disputes that construction. See PO Resp. 12 (adopting our construction); Pet. Reply 1–7 (disputing only the meaning of other claim terms). Thus, we maintain our construction as stated above.” slip op. at 12
- Obviousness (§103) › Motivation to combine / reasonable expectation of successMotivation foundReasonable expectation foundUnpatentable
“Again, we disagree with Consumeron. As Instacart points out, Park’s system and method is not limited to one-hour delivery. See Pet. Reply 19. To the contrary, Park teaches that items can be “delivered within the hour or within a customer specified delivery window” exceeding an hour. Ex. 1005, Abstract (emphasis added), 20:9–12 (describing “processing orders for deferred delivery (i.e. those not required to be delivered in the next hour)” (emphasis added)); see also Ex. 1044 ¶ 29. Moreover, while Park places some emphasis on delivery time, it also explains that its goal is to promote customer satisfaction. See Ex. 1005, 30:16–18 (increasing “dispatch efficiency and customer satisfaction”), 34:5–7 (resequencing delivery “to ensure 100% customer satisfaction”). In that regard, the reason that Instacart articulates for combining Park and Kim dovetails with Park’s objective of improving customer satisfaction by ensuring the product to be delivered is acceptable to the customer. See Ex. 1044 ¶ 65 (“[A] POSITA would have understood that a customer ordering goods would care little if an unacceptable product was delivered quickly.”).” slip op. at 28
Patent outcomesUS 8,244,594 unpatentableClaim construction§ 103 obviousnesscites Phillips · KSRPatents in suitUS 8,244,594 - Maplebear Inc. D/B/A Instacart v. Consumeron, LLCAll claims unpatentablePTAB · Feb 29, 2024 · IPR2022-01358 · APJ Michael A Valek · IPR · Final written decision
Claims 1–5, 8, 9, 12, 14, 18, 19, and 21–28 are unpatentable as obvious over the four asserted combinations of Park and Kim, with Hileman, Mault, or Pugliese where specified.
RulingsFinal written decision- Skill levelSkill level petitioner adoptedDecided for petitioner
“Patent Owner offers a similar description, asserting that a POSITA “is someone with a background in electrical engineering, computer science or the like” and that either experience or training can make up for a lack of the other. Resp. 9–10 (citing Ex. 2016 ¶¶ 17–20). We adopt Petitioner’s definition of the level of ordinary skill in the art. This definition is supported by the record (Ex. 1003 ¶ 24) and consistent with the disclosure in the ’067 patent and the references cited in the Petition. Patent Owner’s definition is “not materially different” from Petitioner’s definition. See Ex. 2016 ¶ 20 (Patent Owner’s declarant acknowledging such). Thus, our analysis and findings would be the same under either sides’ proposal.” slip op. at 8
- Prior constructionPrior construction adoptedDecided for petitioner
“In the institution decision, we agreed with and applied the same MDAS construction adopted by the district court in the Delaware litigation. Dec. 12–14. That is, a “mobile delivery agent system” is “a mobile system that includes at least a device to capture video or still images and a device set up to communicate with a remote server.” Ex. 1034, 1. To the extent there was any substantive disagreement with this preliminary construction, we invited the parties to present their alternative positions at trial. See Dec. 14. Neither party has done so. See Resp. 13 (applying same MDAS construction); Reply 1–5 (addressing other claim construction issues, but not raising any issue with the MDAS construction). Accordingly, we apply the same construction of “mobile delivery agent system” here. ii. “real-time” The term “real-time” is not recited in the independent claims, but does appear in some of the challenged dependent claims. See Ex. 1001, 10:8– 14:16 (claims 14 and 18). In the institution decision, we agreed with and applied the same construction adopted by the district court in the Delaware litigation. Dec. 14–15. That is, that “real-time” has its ordinary meaning, which is “data that is passed along as it is gathered.” Ex. 1034, 2. Neither party has proposed an alternative construction. See Resp. 13 (applying same “real-time” construction); Pet. 14 (asserting that “the terms of the Challenged Claims should be given their ordinary and customary meaning”). Accordingly, we apply the same construction of “real-time” here.” slip op. at 8
- Claim Construction › Intrinsic evidence (Phillips canons) › Plain and ordinary meaning to a POSITATerm construed petitioner constructionDecided for petitioner
“We agree with Petitioner. Contrary to Patent Owner’s assertions, the Specification does not exclusively equate an “acquisition request” with a shopping or purchase request. See Resp. 10–12. Rather, the Specification repeatedly uses the phrasing “purchase or otherwise acquire” to indicate that a delivery agent may acquire goods by means other than purchasing or shopping. See, e.g., Ex. 1001, 5:4–6 (“[T]he user specifies the exact location from which the selected delivery agent is to purchase or otherwise acquire the product, such as a retail store location.”); id. at 7:24–26 (“If the product is approved at 120, the delivery agent will purchase or otherwise acquire the product on behalf of the customer at 121 and deliver the product.”); id. at 2:15–18 (“[T]he user provides the service provider with information regarding the type of product desired and the shopping or acquisition location from which the user desires to purchase or otherwise obtain the product.”). Patent Owner’s argument that the Specification uses the “word ‘or’ to refer to things that are synonymous to each other” is not persuasive. See Resp. 10; Sur-reply 4 (citing Epic Games, Inc. v. Ingeniosh, LLC, IPR2022- 00202, Paper 29, 18–19 (PTAB May 19, 2023)). As noted above, the Specification uses the phrasing “purchase or otherwise acquire.” Ex. 1001, 5:4–6, 7:24–26 (emphasis added); see also id. at 2:15–18 (similar). By including the adverb “otherwise,” the Specification makes clear that purchase and acquire are not used synonymously, but rather that acquiring is broader and encompasses other ways of obtaining a product. See Ex. 1039, 1 (“otherwise” means “in a different way or manner”).” slip op. at 10
- Obviousness (§103) › Motivation to combine / reasonable expectation of successMotivation foundReasonable expectation foundDecided for petitioner
“Petitioner has also articulated a sufficient rationale for combining these elements of Park and Kim. See Pet. 20–23 (citing exhibits). Kim identifies a problem with purchasing a product from a website, i.e., that the product delivered to the customer may not match the images or videos of that product on the website. Ex. 1006, 2. Kim teaches this problem can be overcome by having the delivery service provider operate a MDAS to transmit an image of the actual product in real time to the customer so that after receiving the image the customer can send instructions back to the delivery service provider confirming that is the product they delivered. Id. We credit Dr. Houh’s testimony that, based on these teachings, a POSITA would have been motivated to incorporate those same steps into Park’s system and methodology to “enhance the reliability of the delivery,” “increase customer satisfaction,” and “save[] resources” by preventing the delivery of goods that, upon viewing, the customer might reject. Ex. 1003 ¶¶ 51–56. Moreover, a POSITA would have had a reasonable expectation of success in combining these teachings because Park’s system was already configured to send live video and images to the customer’s computer. Ex. 1003 ¶ 57. Indeed, while Park primarily discusses transmission of video and images of the delivery process to the customer, it expressly teaches that its objective is to “allow customers to interactively view, in real-time, the progress of his order, from reception to compilation to delivery though the route taken by the delivery agent.” Ex. 1005, 4:26–32 (emphasis added). Incorporating Kim’s teachings regarding elements 1.5–1.7 would further this objective, allowing the customer to interactively view images of the actual products compiled for delivery and send instructions back to the delivery agent regarding those products prior to delivery. See Ex. 1003 ¶ 57 (explaining that the combination allows Park’s system to perform the same intended functionality “in a more reliable way”). Accordingly, Petitioner has shown that it would have been obvious to” slip op. at 24
Patent outcomesUS 10,115,067 unpatentableClaim construction§ 103 obviousnesscites Phillips · KSR · GrahamPatents in suitUS 10,115,067 - Maplebear Inc. D/B/A Instacart v. Consumeron, LLCAll claims unpatentablePTAB · Feb 29, 2024 · IPR2022-01359 · APJ Michael A Valek · IPR · Final written decision
Claims 1, 3, 4, and 6–15 are unpatentable as obvious over Park, Kim, and Williams; claims 11–13 are also unpatentable over those references with Hileman.
RulingsFinal written decision- Skill levelSkill level petitioner adoptedDecided for petitioner
“Patent Owner offers a similar description, asserting that a POSITA “is someone with a background in electrical engineering, computer science or the like” and that either experience or training can make up for a lack of the other. Resp. 9–10 (citing Ex. 2016 ¶¶ 17–20). We adopt Petitioner’s definition of the level of ordinary skill in the art. This definition is supported by the record (Ex. 1003 ¶ 24) and consistent with the disclosure in the ’191 patent and the references cited in the Petition. Patent Owner’s definition is “not materially different” from Petitioner’s definition. See Ex. 2016 ¶ 20 (Dr. Mitzenmacher acknowledging such). Thus, our analysis and findings would be the same under either sides’ proposal.” slip op. at 9
- Prior constructionPrior construction adoptedDecided for petitioner
“ii. “real-time” In the institution decision, we agreed with and applied the same construction adopted by the district court in the Delaware litigation. Dec. 14–15. That is, that “real-time” has its ordinary meaning, which in this context is “data that is passed along as it is gathered.” Ex. 1034, 2. Notably, this is the same construction Patent Owner advocated for in the Delaware litigation. See Ex. 1035, 4. Nevertheless, Patent Owner now seeks to add to that construction, urging that the district court “accepted” that the term “does not include any ‘intentional delay’ in the transmission.” Resp. 14 (citing Ex. 1035, 22, 26); see also Sur-reply 16–17 (essentially same). Although the district court considered “intentional delay” in the course of construing “real time,” it did not include the additional language Patent Owner proposes in its construction. See Ex. 1035, 2. Moreover, the district court stated it “sees no reason that a ‘real-time’ transmission of data could not both involve no inherent delay and permit a system that requires multiple ‘clicks’ to operate.” Id. at 25 (emphasis added). In addition, the district court quoted from a technical dictionary, which provided: The basic definition of real-time data is that it is data that is not kept or stored, but is passed along to the end user as quickly as it is gathered. It is important to note that real-time data does not mean that the data gets to the user instantly. There may be any number of bottlenecks related to the data collection infrastructure, the bandwidth between various parties, or even just the slowness of the end user’s computer. Real-time data does not promise data within a certain number of microseconds. It just means that the data is not designed to be kept back from its eventual use as it is collected. Id. at 26 (citing “Technopedia”). In other words, the district court contemplated that real-time data” slip op. at 10
- Claim Construction › Intrinsic evidence (Phillips canons) › Plain and ordinary meaning to a POSITATerm construed petitioner constructionDecided for petitioner
“We agree with Petitioner. Contrary to Patent Owner’s assertions, the Specification does not exclusively equate an “acquisition request” with a shopping or purchase request. See Resp. 10–12. Rather, the Specification repeatedly uses the phrasing “purchase or otherwise acquire” to indicate that a delivery agent may acquire goods by means other than purchasing or shopping. See, e.g., Ex. 1001, 5:4–6 (“[T]he user specifies the exact location from which the selected delivery agent is to purchase or otherwise acquire the product, such as a retail store location.”); id. at 7:24–26 (“If the product is approved at 120, the delivery agent will purchase or otherwise acquire the product on behalf of the customer at 121 and deliver the product.”); id. at 2:15–18 (“[T]he user provides the service provider with information regarding the type of product desired and the shopping or acquisition location from which the user desires to purchase or otherwise obtain the product.”). Patent Owner’s argument that the Specification uses the “word ‘or’ to refer to things that are synonymous to each other” is not persuasive. See Resp. 10; Sur-reply 4 (citing Epic Games, Inc. v. Ingeniosh, LLC, IPR2022- 00202, Paper 29, 18–19 (PTAB May 19, 2023)). As noted above, the Specification uses the phrasing “purchase or otherwise acquire.” Ex. 1001, 5:4–6, 7:24–26 (emphasis added); see also id at 2:15–18 (similar). By including the adverb “otherwise,” the Specification makes clear that purchase and acquire are not used synonymously, but rather that acquiring is broader and encompasses other ways of obtaining a product. See Ex. 1039, 1 (“otherwise” means “in a different way or manner”).” slip op. at 12
- Obviousness (§103) › Motivation to combine / reasonable expectation of successMotivation foundReasonable expectation foundUnpatentable
“Petitioner has also articulated a sufficient rationale for combining these elements of Park and Kim. See Pet. 22–25 (citing exhibits). Kim identifies a problem with purchasing a product from a website, i.e., that the product delivered to the customer may not match the images or videos of that product on the website. Ex. 1006, 2. Kim teaches this problem can be overcome by having the delivery service provider operate a MDAS to transmit an image of the actual product in real time to the customer so that after receiving the image the customer can send instructions back to the delivery service provider confirming that is the product they delivered. Id. We credit Dr. Houh’s testimony that, based on these teachings, a POSITA would have been motivated to incorporate those same steps into Park’s system and methodology to “enhance the reliability of the delivery,” “increase customer satisfaction,” and “save[] resources” by preventing the delivery of goods that, upon viewing, the customer might reject. Ex. 1003 ¶¶ 62–67. Moreover, a POSITA would have had a reasonable expectation of success in combining these teachings because Park’s system was already configured to send live video and images to the customer’s computer. Ex. 1003 ¶ 69. Indeed, while Park primarily discusses transmission of video and images of the delivery process to the customer, it expressly teaches that its objective is to “allow customers to interactively view, in real-time, the progress of his order, from reception to compilation to delivery though the route taken by the delivery agent.” Ex. 1005, 4:26–32 (emphasis added). reach Petitioner’s backup argument that this “clause . . . is a non-limiting statement of intended purpose.” See Reply 15–17; Tr. 29:12–30:6 (Petitioner acknowledging this is a “backup position”). Incorporating Kim’s teachings regarding elements 1.3–1.5 would further this objective, allowing the customer to interactively view images of the actual products compiled for delivery and, if acceptable, send approval for the delivery agent to purchase and deliver those goods. See Ex. 1003 ¶ 68 (explaining that the combination allows Park’s system to perform the same intended functionality “in a more reliable way”).” slip op. at 31
Patent outcomesUS 9,202,191 unpatentableClaim construction§ 103 obviousnesscites Phillips · KSR · GrahamPatents in suitUS 9,202,191 - Parse Biosciences, Inc. v. 10x Genomics, Inc.Rehearing grantedPTAB · Feb 5, 2024 · IPR2023-00958 · APJ Michael J Fitzpatrick · IPR · Rehearing
Rehearing was granted and IPR instituted on claims 1–28 because the petition showed a reasonable likelihood that claim 1 was obvious over Linnarsson, McCloskey, and ordinary skill.
RulingsRehearing decision- RehearingRehearing, grantedGranted
“III. WHETHER REHEARING IS WARRANTED Petitioner argues that we misconstrued the claims “as requiring one to add tags in a way that can provide a distinction based on a ‘polynucleotide sequence.’” Req. 6 (quoting Dec. 14 (Petitioner’s emphasis)). Petitioner is correct. More specifically, we implicitly construed the claim language reciting “a second tag sequence distinguishing said sample polynucleotide from other sample polynucleotides from said cell,” as requiring said “distinguishing” to be based on the sequences of the sample polynucleotides. See, e.g., Dec. 14 (“[E]ach strand of cDNA that is tagged in Linnarsson is tagged regardless of the polynucleotide sequence of the cDNA or its corresponding mRNA. Thus, Linnarsson’s tags do not distinguish between ‘sample polynucleotides,’ whether cDNA or mRNA, of different sequences.”). Based on that misunderstanding, we erroneously determined that the proposed modification could not achieve the claim language, stating the following: Petitioner’s proposal appears to defeat satisfaction of another portion of claim 1, namely a “second tag sequence distinguishing said sample polynucleotide from other sample polynucleotides from said cell.” Ex. 1001, 30:62–64. For if the second tag is “added to the CDS or TSO after extension,” as opposed to the sample polynucleotide, as Petitioner argues (Pet. 39 (emphasis added)), it would appear that the second tag would be incapable of distinguishing any sample polynucleotide from other sample polynucleotides. Rather, the second tag would be ligated to each and every extension product bearing a CDS or TSO without regard to the sequence of any sample polynucleotide. Dec. 16. We now reconsider whether to institute.” slip op. at 2
- PTAB / AIA Trials › Discretionary denial › §325(d) same art / argumentsDecided for petitioner
“Cited”). Because we find that the same or substantially the same art was previously presented to the Office, we proceed to part two of the analysis. 2. Advanced Bionics Part Two Patent Owner argues that the Petition “fails to show any error in the Examiner’s application during prosecution of the prior art teachings Petitioner now purports to invoke from . . . McCloskey.” Prelim Resp. 23; see also id. at 24–25 (“Revisiting the same art and arguments already overcome during prosecution is a waste of the Board’s limited resources and would unfairly burden PO.”). However, Petitioner argued that “the Examiner committed major error in Examination by erroneously stating that the prior art fails to teach a dual tagging approach when, in fact, this approach is plainly taught in both McCloskey and McCloskey II.” Pet. 67. The record supports Petitioner’s position, and we agree that the error was material to patentability. See Ex. 1005, 131 (Notice of Allowance). Accordingly, and having considered all of the Becton, Dickinson factors, we do not exercise discretionary denial.” slip op. at 12
- PTAB / AIA Trials › Institution threshold (reasonable likelihood / more likely than not)InstitutedInstituted
“We are persuaded there is a reasonable likelihood that Petitioner would prevail in demonstrating that a person of ordinary skill in the art would have had a reasonable expectation of success in combining the teachings of Linnarsson and McCloskey with the knowledge of a person of ordinary skill in the art to obtain the claimed subject matter. 8. Conclusion as to Claim 1 There is a reasonable likelihood that Petitioner would prevail in proving that claim 1 is unpatentable.” slip op. at 21
- Obviousness (§103) › Analogous artNot reached
“the three references is analogous art to the ’013 patent as opposed to each other. Prelim. Resp. 46 (citing Pet. 35; Sanofi-Aventis Deutschland GmbH v. Mylan Pharms. Inc., 66 F.4th 1373, 1374 (Fed. Cir. 2023)). As Sanofi- Aventis holds, a petitioner bears the burden of persuasion to establish that an asserted prior art reference is analogous art to the claimed invention. See Sanofi-Aventis, 66 F.4th at 1377 (“We agree with [the patent owner] that [the petitioner] did not carry its burden to argue that de Gennes is analogous to the [challenged] patent.”); id. (“In evaluating whether a reference is analogous, we have consistently held that a patent challenger must compare the reference to the challenged patent.”); id. at 1378–79 (“We have routinely held that the petitioner has the burden of proving unpatentability.”). However, the Petition should not be denied for failing to state explicitly that the cited prior art references are analogous art to the ’013 patent. Rather, as Sanofi-Aventis further held: “A petitioner is not required to anticipate and raise analogous art arguments in its petition; instead a petitioner can use its reply to ‘respond to arguments raised in the corresponding opposition, patent owner preliminary response, patent owner response, or decision on institution.’” Sanofi-Aventis, 66 F.4th at 1379 (quoting 37 C.F.R. § 42.23). Accordingly, we need not address this issue for purposes of deciding whether to institute trial.” slip op. at 15
§ 103 obviousnessDiscretionary denialPatents in suitUS 10,697,013 - Parse Biosciences, Inc. v. 10x Genomics, Inc.Rehearing grantedPTAB · Feb 5, 2024 · IPR2023-00955 · APJ Michael J Fitzpatrick · IPR · Rehearing
Rehearing granted and IPR instituted on claims 1–26; the Board found a reasonable likelihood that claim 1 would have been obvious over Linnarsson and McCloskey.
RulingsRehearing decision- RehearingRehearing, grantedGranted
“III. WHETHER REHEARING IS WARRANTED Petitioner argues that we misconstrued the claims “as requiring one to add tags in a way that can ‘provide a distinction based on a polynucleotide’s sequence.’” Req. 6 (quoting Dec. 15 (Petitioner’s emphasis)). Petitioner is correct. More specifically, we implicitly construed the claim language reciting “a second tag sequence distinguishing said sample polynucleotide from other sample polynucleotides from said cell,” as requiring said “distinguishing” to be based on the sequences of the sample polynucleotides. See, e.g., Dec. 14 (“[E]ach strand of cDNA that is tagged in Linnarsson is tagged regardless of the polynucleotide sequence of the cDNA or its corresponding mRNA. Thus, Linnarsson’s tags do not distinguish between ‘sample polynucleotides,’ whether cDNA or mRNA, of different sequences.”). Based on that misunderstanding, we denied the Petition because “adding a second tag sequence to Linnarsson’s CDS and/or TSO would do nothing to achieve such a distinction,” i.e., “a distinction based on a polynucleotide’s sequence.” Id. at 15. That was error. We now reconsider whether to institute.” slip op. at 2
- PTAB / AIA Trials › Discretionary denial › §325(d) same art / argumentsInstitution denied 325dDecided for petitioner
“the ’197 patent. See Ex. 1001, code (56) (listing McCloskey II under “References Cited”). Because we find that the same or substantially the same art was previously presented to the Office, we proceed to part two of the analysis.” slip op. at 11
- PTAB / AIA Trials › Institution threshold (reasonable likelihood / more likely than not)InstitutedInstituted
“We are persuaded there is a reasonable likelihood that Petitioner would prevail in demonstrating that a person of ordinary skill in the art would have had a reasonable expectation of success in combining the teachings of Linnarsson and McCloskey to obtain the claimed subject matter. 6. Conclusion as to Claim 1 There is a reasonable likelihood that Petitioner would prevail in proving that claim 1 is unpatentable.” slip op. at 18
- Obviousness (§103) › Analogous artNot reached
“GmbH v. Mylan Pharms. Inc., 66 F.4th 1373, 1374 (Fed. Cir. 2023)). As Sanofi-Aventis holds, a petitioner bears the burden of persuasion to establish that an asserted prior art reference is analogous art to the claimed invention. See Sanofi-Aventis, 66 F.4th at 1377 (“We agree with [the patent owner] that [the petitioner] did not carry its burden to argue that de Gennes is analogous to the [challenged] patent.”); id. (“In evaluating whether a reference is analogous, we have consistently held that a patent challenger must compare the reference to the challenged patent.”); id. at 1378–79 (“We have routinely held that the petitioner has the burden of proving unpatentability.”). However, the Petition should not be denied for failing to state explicitly that the cited prior art references are analogous art to the ’197 patent. Rather, as Sanofi-Aventis further held: “A petitioner is not required to anticipate and raise analogous art arguments in its petition; instead a petitioner can use its reply to ‘respond to arguments raised in the corresponding opposition, patent owner preliminary response, patent owner response, or decision on institution.’” Sanofi-Aventis, 66 F.4th at 1379 (quoting 37 C.F.R. § 42.23). Accordingly, we need not address this issue for purposes of deciding whether to institute trial.” slip op. at 15
§ 103 obviousnessDiscretionary denialPatents in suitUS 10,240,197 - PTAB · Feb 1, 2024 · IPR2023-01298 · APJ Devon Zastrow Newman · IPR · Institution
The Board instituted IPR on claims 1–30 and all asserted grounds, finding a reasonable likelihood that Chell anticipates at least one claim.
RulingsInstitution decision- PTAB / AIA Trials › Institution threshold (reasonable likelihood / more likely than not)InstitutedInstituted
“partes review may not be instituted “unless . . . there is a reasonable likelihood that the petitioner would prevail with respect to at least 1 of the claims challenged in the petition.” 35 U.S.C. § 314(a). The Board determines whether to institute a trial on behalf of the Director. 37 C.F.R. § 42.4(a). A decision to institute is “a simple yes-or-no institution choice respecting a petition, embracing all challenges included in the petition.” PGS Geophysical AS v. Iancu, 891 F.3d 1354, 1360 (Fed. Cir. 2018).” slip op. at 2
- Skill levelSkill level petitioner adoptedDecided for petitioner
“would have possessed a strong understanding in the use and development of genetics and genomics approaches for detecting or monitoring human diseases, such as spatial detection of a target analyte (e.g., mRNA or DNA) in a tissue, and would typically have a Ph.D. in a relevant field (e.g., molecular biology, genetics, and bioinformatics) with two years of experience. Pet. 14 (citing Ex. 1002 ¶¶ 24–25). For the purposes of its Preliminary Response, Patent Owner does not provide its own proposed level of skill. Prelim. Resp. 10. For purposes of this Decision, we apply Petitioner’s unchallenged definition as it is consistent with the cited prior art and disclosure of the ’689 patent.” slip op. at 12
- Claim Construction › Intrinsic evidence (Phillips canons) › Plain and ordinary meaning to a POSITATerm construed board ownOther
“a) contacting the tissue sample with a plurality of nucleic acid probes, wherein each of the nucleic acid probes comprise a target binding domain that binds to the at least one target analyte, wherein the tissue sample [has been] is treated to facilitate binding of the nucleic acid probes to the target analyte b/c) collecting the nucleic acid probes, or portions thereof, bound to the at least one target analyte in a first/second location of the tissue sample under conditions that release the nucleic acid probes, or portions thereof, from the first/second location of the tissue sample d/e) performing an extension reaction that incorporates at least one nucleic acid sequence that identifies the first/second location of the tissue sample into each of the nucleic acid probes, or portions thereof, collected in step (b), thereby forming a first plurality of extension products that comprise the nucleic acid probes, or portions thereof, collected in step (b) and the at least one nucleic acid sequence that identifies the first/second location of the tissue sample Ex. 1001, 145:51–147:11 (emphasis added). Thus, according to claim 1, the “nucleic acid probe” must 1) comprise a target binding domain that binds to the at least one target analyte, 2) be bound to the at least one target analyte; 3) be released in whole or as a portion, and 4) have a location-identifying nucleic acid sequence incorporated into it through an extension reaction. Steps a), b), and c) occur in relation to the target analyte, while steps d) and e) occur after the probe is” slip op. at 21
- Novelty / Anticipation (§102) › Anticipation standard (single reference, every element)Not shown unpatentableNot shown unpatentable
“We further interpret “collecting the nucleic acid probes” to mean “releasing all or a portion of the nucleic acid probe bound to the at least one target analyte through application of a force followed by retrieval of the released probe or portion of the probe.” The question then becomes whether So-465, which teaches replication of a probe that was bound and then at least partially released to make genomic amplicons, followed by collection of those genomic amplicons, anticipates collection of probes as recited in claims 1 and 16. On this record, we do not see sufficient evidence that the genomic amplicons disclosed in So-456 that Petitioner identifies as “captured” were ever “bound to the analyte” in part or in whole as required by the claim language, but rather were amplified in situ from the probe or partial probe that was released. Ex. 1005 ¶¶ 181–183. In particular, the process of So-456 differs from the ’689 patent claims in that the extension reaction to incorporate the tissue-identifying nucleic acid sequence in So-465 occurs after the identifier nucleotide is cleaved from the tissue sample. “Anticipation requires that all of the claim elements and their limitations are shown in a single prior art reference.” In re Skvorecz, 580 F.3d 1262, 1266 (Fed. Cir. 2009). Petitioner has not demonstrated that So-456 teaches this claim limitation or otherwise demonstrates that this limitation would have been inherent in the disclosure of So-456 for claims 1 and 16. For these reasons, on this record we determine that Petitioner has not shown a reasonable likelihood that So-456 anticipates either of independent claims 1 or 16.” slip op. at 24
Claim construction§ 102 anticipation§ 103 obviousnesscites GrahamPatents in suitUS 11,377,689 - PTAB · Feb 1, 2024 · IPR2023-01254 · APJ Ryan H Flax · IPR · Institution
The Board instituted IPR on claims 1, 2, and 5–18 on all six asserted grounds, finding a reasonable likelihood of unpatentability under at least one ground.
RulingsInstitution decision- PTAB / AIA Trials › Institution threshold (reasonable likelihood / more likely than not)InstitutedInstituted
“institute trial in an inter partes review. We may institute an inter partes review if the information presented in the petition filed under 35 U.S.C. § 311, and any preliminary response filed under § 313, shows that there is a reasonable likelihood that Petitioner would prevail with respect to at least one of the claims challenged in the petition. 35 U.S.C. § 314. After reviewing the parties’ submissions in view of the preliminary record, we conclude Petitioner demonstrates a reasonable likelihood it would prevail in showing that at least one challenged claim of the ’332 patent is unpatentable under the presented grounds. See Pet.; Prelim. Resp.” slip op. at 2
- Skill levelSkill level petitioner adoptedDecided for petitioner
“ORDINARY LEVEL OF SKILL IN THE ART Petitioner contends: A POSITA,[11] on or before August 17, 2007, or alternatively on or before April 11, 2008, would have had a minimum of a Bachelor’s degree in Industrial Design, Mechanical Engineering, or related field and approximately 5 years of professional experience in the field of consumer product design and manufacturing. Additional graduate education could substitute for professional experience, or significant experience in the field could substitute for formal education. Pet. 4 (citing Ex. 1008 ¶ 44).” slip op. at 10
- Claim Construction › Threshold & procedure › Whether a term needs construction (O2 Micro)No construction neededOther
“CLAIM CONSTRUCTION Petitioner asserts that the claim language “angled capsule retaining elements” is a means-plus-function limitation under 35 U.S.C. § 112(6), where the function is “retaining an oral care capsule in a capsule receiving zone,” and the Specification’s corresponding structure is “angled bristles.” Pet. 8–11 (citing Ex. 1001, Abstract, 2:59–61, 2:65–67, 3:20–22, 4:64–5:13, 6:23–24, 6:26–30, 6:34–37, 7:19–23, 7:33–42, 9:61–10:1, 10:5–8, Figs. 1, 4, 5, 6; Ex. 1002, 224; Ex. 1008 ¶¶ 96–97). Petitioner argues that “angled capsule retaining elements” is non- structural and includes the generic placeholder nonce word “elements,” modified by functional language, and the claim does not further recite sufficiently definite structure for the elements. Id. at 8–9. Thus, it is Petitioner’s position that this limitation, although not using the presumptive word “means,” should be interpreted to be a means-plus-function limitation. Further, Petitioner argues that the only structure disclosed in the ’332 patent’s Specification that performs the claimed function is “angled bristles,” and that the Specification’s express mentioning of the term “retaining element” relates to a non-claimed feature having a different function, i.e., a movable back cover on the toothbrush to contain rear-loaded capsules in the head. Id. at 11 (discussing Ex. 1001, 5:10–19, 6:8–25; Ex. 1002, 228, 353–355). Patent Owner does not directly address Petitioner’s claim construction position. See generally Prelim. Resp. However, even if not addressing whether the claim language is a means-plus-function limitation, Patent Owner appears to agree with Petitioner that the claims’ scope includes angled bristles as the recited retaining elements, as disclosed in the Specification, although not expressly conceding at this point that the claims are limited to the disclosed angled bristles structure and equivalents under 35 U.S.C. § 112(6). See id. at 3–4 (citing paragraph 36 and Figure 1 of the application that issued as the ’332 patent). For the purposes of this institution decision, we find it unnecessary to construe any claim language because there is no dispute that the “angled capsule retaining elements” limitation recited by the claims includes angled bristles, even if it may not be limited to only such a structure (and its equivalents), and we find that angled bristles appear to be taught in the prior art, as discussed below. See Nidec Motor Corp. v. Zhongshan Broad Ocean Motor Co., 868 F.3d 1013, 1017 (Fed. Cir. 2017) (“[W]e need only construe terms ‘that are in controversy, and only to the extent necessary to resolve the controversy.’” (quoting Vivid Techs., Inc. v. Am. Sci. & Eng’g, Inc., 200 F.3d 795, 803 (Fed. Cir. 1999)). Thus, whether or not the disputed claim language constitutes a means-plus-function limitation is not determinative at this stage of the proceeding.” slip op. at 11
- Obviousness (§103) › Graham factors (scope of art, differences, level of skill)Motivation foundReasonable expectation foundInstituted
“2. Analysis We find that, on the current record, Petitioner has sufficiently mapped the limitations of the claims to the disclosures of Wolcott, Davidson, and Fitz-Gibbon, identified a reason with rational underpinnings why the ordinarily skilled artisan would have combined the teachings of the 15 Although we note that Patent Owner submits no supporting evidence, we do so with the understanding that Patent Owner was not required to do so, as the burden here is upon, and remains with, Petitioner. references, and identified that there would have been a reasonable expectation of success.” slip op. at 26
Claim construction§ 103 obviousnesscites GrahamPatents in suitUS 8,881,332 - Twinstrand Biosciences, Inc. v. Guardant Health, Inc.No claims unpatentablePTAB · Jan 26, 2024 · IPR2022-01400 · APJ Michael A Valek · IPR · Final written decision
Claims 1–29 were not shown unpatentable over the asserted obviousness grounds because the prior-art combinations did not teach key limitations of claims 1, 17, and 29.
RulingsFinal written decision- BurdenNot shown unpatentable
“Having considered these arguments on the full trial record, we find Patent Owner has the better position because Petitioner’s showing that element 1(b) is taught by Schmitt is unpersuasive. We begin with Patent Owner’s argument concerning the distinction between the cfDNA molecules and the duplex tag comprising the molecular barcode found in the text of claim 1. Element 1(a) recites “a population of cell-free deoxyribonucleic acid (cfDNA) molecules.” Ex. 1001, 61:7–9. Element 1(b) recites “tagging a plurality of the cfDNA molecules in the population” of element 1(a) “with duplex tags comprising molecular barcodes to produce tagged parent polynucleotides . . . wherein the duplex tags are attached to both ends of a added). We agree with Patent Owner and credit the testimony of its declarant that this claim language distinguishes the duplex tags from the ends of the cfDNA molecule to which they are attached. Resp. 8; Ex. 2015 ¶¶ 38–39, 60, 61. That is, the duplex tag is not part of the cfDNA molecule itself, but rather is “attached to both the ends” of that molecule by “tagging” it as recited in element 1(b). We also agree with Patent Owner that given this distinction, claim 1 does not encompass Schmitt’s hybrid embodiment. Resp. 18–20. As Petitioner notes, “[i]n Schmitt’s hybrid-tag embodiment, the strands are grouped based on the combination of the short n-mer barcode and the end of the target DNA.” Pet. 11; see Resp. 17 (“[T]he combination of the endogenous shear sequence and exogenous 3-mer sequence together provide the SMI used for grouping and matching in Schmitt’s DCS process.”). Petitioner and its declarant illustrate the grouping in Schmitt’s hybrid embodiment with the following diagram. Pet. 12; Ex. 1002 ¶¶ 96–98. Petitioner’s diagram shows the PCR products produced from sequencing a “Target DNA” molecule that has been tagged with 3-mers X and Y according to Schmitt’s hybrid embodiment. See Ex. 1002 ¶ 98 (describing diagram). A portion of the endogenous sequence of the DNA molecule labeled L and R is used in combination with the 3-mer sequence to group the resulting strands into two families labeled the “X+L→R+Y Family” and the “R+Y→X+L Family.” Ex. 1002 ¶ 98; Ex. 2015 ¶ 62 (explaining that Petitioner’s diagram shows that “the relied upon hybrid SMI sequences of Schmitt include sequence from the sample DNA molecule not contained in the adapter or the duplex tags”). SMIs, differently label the strands and therefore are the recited “duplex tags.” See Pet. 27–28 (“duplex tags comprise both the fragment DNA end sequences and a shorter n-mer tag”) (emphasis added) (internal quotations omitted). However, we credit Dr. Quackenbush’s testimony that end sequences L and R are not “attached to both ends” of the cfDNA molecule by “tagging” it as recited in element 1(b). See Ex. 2015 ¶ 59–62 (explaining that Schmitt’s hybrid SMI sequences include a portion of the sample DNA molecule, which is “not contained in adapter molecules or duplex tags that are attached to the DNA molecules”). Rather, end sequences L and R are the pre-existing, endogenous ends of that molecule. Id. Thus, Petitioner’s theory of unpatentability does not account for the distinction the claim language draws between the cfDNA molecule and the duplex tags. Petitioner’s argument that the ’306 patent defines “duplex tag” as a” slip op. at 20
- Obviousness (§103) › Motivation to combine / reasonable expectation of successNot shown unpatentableNot shown unpatentable
“That is, although Meyer teaches that its particular protocol results in 40–60% tagging efficiency, Petitioner has not sufficiently explained why a person of ordinary skill in the art would have expected Meyer’s tagging efficiency to apply to Schmitt’s DCS method when used with Narayan’s sequencing of cfDNA. For example, the Petition does not address the differences between Meyer’s adapters and Schmitt’s adapters and how those differences affect the tagging efficiency. Meyer’s barcodes comprise “single self-hybridized palindromic oligonucleotides, carrying an Srf I restriction site in the middle (GCCCGGGC), a sequence tag at the 3’ end and the reverse complementary tag sequence at the 5’ end.” Ex. 1005, Fig. 1. Schmitt, on the other hand, teaches a “hybrid method” of tagging that uses a combination of the sheared ends of the DNA fragments and a “shorter n-mer tag (such as 1 or 2 or 3 or 4 or more degenerate or semi degenerate bases) in the adaptor.” Ex. 1083 ¶ 30. sticky-end adapter-DNA litigation to be even more efficient than Meyer’s blunt-end adapter-DNA ligation” is also unpersuasive. See Pet. 60–61. The KAPA data sheet discloses sticky-end adapter DNA ligation, but KAPA teaches that only 0.5 to 15% tagging efficiency is expected when the starting sample is 100 pg–100 ng of “high quality DNA.” Ex. 1015, 4. Thus, the KAPA data suggests that the use of sticky-end adapters, such as what Schmitt discloses, does not in and of itself teach or suggest the tagging efficiency limitations. Moreover, the record shows that tagging efficiency depends on a variety of other factors, including the quality of the input DNA. The KAPA data sheet states that tagging efficiency “can be significantly lower for DNA of lower quality.” Ex. 1015, 4. Fisher also explains that “the efficiency of adaptor ligation varies between samples, probably because of variation in input DNA quality.” Ex. 1031, 5–6. Petitioner’s argument that the DNA the KAPA data sheet refers to as “lower quality” is “from formalin-fixed, paraffin-embedded (‘FFPE’) samples (well known for having chemically damaged DNA)” is unavailing. See Reply 25–26 (citing Ex. 1098 ¶¶ 96–98). First, neither Petitioner, nor its declarant, address the similar teaching in Fisher. Second, even if the specific type of lower quality DNA in the KAPA data sheet is different, the salient point, i.e., that tagging efficiency depends on DNA quality, remains unrebutted. This is significant because Petitioner does not sufficiently address how the quality of the cfDNA of Narayan compares to the quality of the genomic DNA samples of Meyer and Schmitt or how that would affect the expected tagging efficiency. Petitioner’s assertion that “significant quantities of cfDNA could be isolated from blood samples” (see Reply 26), fact that a significant quantity of cfDNA could be obtained does not show that the quality of that DNA is similar such that a POSA using such would have expected to achieve a tagging efficiency similar to that in Meyer.” slip op. at 40
- Strike new argumentNew argument disregardedDenied
“We are not persuaded. First, this is an inappropriate new argument. The Petition presents a different mapping, alleging that the “duplex tag” comprises both the endogenous end sequence of the cfDNA molecule and the 3-mer barcode of Schmitt’s hybrid tag embodiment. Pet. 27 (“the duplex tags comprise both the fragment DNA end sequences and ‘a shorter n-mer tag’ to serve as ‘unique molecular identifiers’”) (quoting Ex. 1083 ¶ 30, Ex. 1002 ¶¶ 162–163); see also Tr. 62:13–63:19 (Petitioner’s counsel noting he was unaware of any explicit statement in the Petition that Schmitt’s duplex tag comprised just the 3-mer without the end sequence). Nor did Petitioner regarding element 1(b). See Reply 8–10. Rather, consistent with the mapping in the Petition, the Reply identifies “Schmitt’s hybrid tags,” i.e., the combination of the endogenous end sequence and the n-mer, as the duplex tags in element 1(b). See Reply 8 (urging that “duplex tags” are “tags that differently label the complementary strands,” which “is precisely what Schmitt’s hybrid tags do”). Because this argument was not previously presented, Patent Owner has not been afforded a sufficient opportunity to address it. Thus, Petitioner’s new argument excluding the end sequences in Schmitt’s hybrid tag embodiment from the alleged “duplex tags comprising molecular barcodes” has been waived. Second, even if we were to consider it on the merits, Petitioner’s new mapping for element 1(b) is inconsistent with Petitioner’s allegations for element 1(e). Element 1(e) recites “reducing or tracking redundancy” in sequence reads “using at least sequencing information from the molecular barcodes of the duplex tags to determine distinct cfDNA molecules.” Ex. 1001, 61:26–30. For these limitations, the Petition points to Schmitt’s grouping of reads into families based on their SMI and asserts that Schmitt determines distinct cfDNA molecules based on “the complementary nature of the SMI on the two strands of the duplex.” See Pet. 30–32 (internal quotations omitted). Thus, like Petition’s mapping for element 1(b), Petitioner’s allegations for element 1(e) rely on a duplex tag that includes both the 3-mer and the end sequence of the cfDNA molecule. Petitioner has not sufficiently explained, much less shown by a preponderance of the evidence, that Schmitt teaches or suggests the limitations in element 1(e) based on its new mapping of the 3-mer alone as duplex tags.” slip op. at 25
- PTAB / AIA Trials › Other PTAB motions (exclude, strike, seal, additional discovery, rehearing)Motion to exclude, deniedDenied
“We do not rely on any of these exhibits in rendering our decision on Petitioner’s grounds. Therefore, we dismiss as moot Petitioner’s motion to exclude Exhibits 1069, 1074, 1078, 1079, and 1085–1088.” slip op. at 46
Patent outcomesUS 11,149,306 not shown unpatentable§ 103 obviousnesscites Phillips · KSR · GrahamPatents in suitUS 11,149,306 - Parse Biosciences, Inc. v. 10x Genomics, Inc.Institution deniedPTAB · Dec 18, 2023 · IPR2023-00955 · APJ Michael J Fitzpatrick · IPR · Institution
The Board denied institution because Petitioner did not show a reasonable likelihood that any challenged claim would be obvious, including a reasonable expectation of success in adding a distinguishing second tag.
RulingsInstitution decision- PTAB / AIA Trials › Institution threshold (reasonable likelihood / more likely than not)Institution denied meritsInstitution denied
“In an inter partes review, it is the Petitioner’s “burden to demonstrate both that a skilled artisan would have been motivated to combine the teachings of the prior art references to achieve the claimed invention, and that the skilled artisan would have had a reasonable expectation of success in doing so.” In re Magnum Oil Tools Int’l, Ltd., 829 F.3d 1364, 1381 (Fed. Cir. 2016) (quotation marks and citations omitted). Based on the information presented here, there is not a reasonable likelihood of Petitioner prevailing in showing that a skilled artisan, even if motivated to combine the teachings of the prior art references as proposed by Petitioner, would have had a reasonable expectation of success in achieving the claimed invention, including “a second tag sequence distinguishing said sample polynucleotide from other sample polynucleotides from said cell.”” slip op. at 16
- Obviousness (§103) › Motivation to combine / reasonable expectation of successNot reached
“In an inter partes review, it is the Petitioner’s “burden to demonstrate both that a skilled artisan would have been motivated to combine the teachings of the prior art references to achieve the claimed invention, and that the skilled artisan would have had a reasonable expectation of success in doing so.” In re Magnum Oil Tools Int’l, Ltd., 829 F.3d 1364, 1381 (Fed. Cir. 2016) (quotation marks and citations omitted). Based on the information presented here, there is not a reasonable likelihood of Petitioner prevailing in showing that a skilled artisan, even if motivated to combine the teachings of the prior art references as proposed by Petitioner, would have had a reasonable expectation of success in achieving the claimed invention, including “a second tag sequence distinguishing said sample polynucleotide from other sample polynucleotides from said cell.”” slip op. at 16
§ 103 obviousnesscites GrahamPatents in suitUS 10,240,197
Holdings, summaries, rulings, issues, outcomes, winners and claim constructions shown for a decision were generated by a large language model reading the opinion. They are a guide to the decision, not the decision. Confirm every one against the court's own text before relying on it. Outcomes read from the patent owner’s side. Party names are extracted from the decision and are missing on about 900 short Director denials and scans, which carry the trial number instead.